abstract：:Averaged single trials (AST) allowed the functional magnetic resonance imaging (fMRI) response to auditory stimuli to be measured at high temporal (1 s) and spatial (0.1 cm3) resolution. Using this paradigm we investigated the transient signal response to 100-ms tone bursts in trains of between 100 ms and 25.5 s in to...

journal_title：NeuroImage

authors： Robson MD,Dorosz JL,Gore JC

更新日期：1998-04-01 00:00:00

abstract：:We present an approach to characterizing the differences among event-related hemodynamic responses in functional magnetic resonance imaging that are evoked by different sorts of stimuli. This approach is predicated on a linear convolution model and standard inferential statistics as employed by statistical parametric ...

journal_title：NeuroImage

authors： Friston KJ,Fletcher P,Josephs O,Holmes A,Rugg MD,Turner R

更新日期：1998-01-01 00:00:00

abstract：:This paper investigates the relationship between the blood oxygenation level dependent (BOLD) contrast effect and regional cerebral blood flow using the techniques of functional MRI (fMRI) and positron emission tomography (PET). A passive listening paradigm with parametric variation in word presentation rate was used ...

journal_title：NeuroImage

authors： Rees G,Howseman A,Josephs O,Frith CD,Friston KJ,Frackowiak RS,Turner R

更新日期：1997-11-01 00:00:00

abstract：:Functional magnetic resonance imaging (fMRI) techniques, such as echo-planar imaging, can permit rapid, sensitive, whole-brain measurements of local blood flow-induced MR signal changes seen during cognitive paradigms. Changes in blood oxygenation due to mismatch of flow and oxygen metabolism cause dynamic variations ...

journal_title：NeuroImage

authors： Ojemann JG,Akbudak E,Snyder AZ,McKinstry RC,Raichle ME,Conturo TE

更新日期：1997-10-01 00:00:00

abstract：:This paper presents the conjecture that functional integration may be mediated by the mutual induction and maintenance of stereotyped spatiotemporal patterns of activity (i.e., transients) in different neuronal populations. In contradistinction to temporal and rate coding models of neuronal interactions, transient cod...

journal_title：NeuroImage

authors： Friston KJ

更新日期：1997-04-01 00:00:00

abstract：:Within the framework of statistical mapping, there are up to now only two tests used to assess the regional significance in functional images. One is based on the magnitude of the foci and tends to detect high intensity signals, while the second is based on the spatial extent of regions defined by a simple thresholdin...

journal_title：NeuroImage

authors： Poline JB,Worsley KJ,Evans AC,Friston KJ

更新日期：1997-02-01 00:00:00

abstract：:We have used the technique of positron emission tomography to study and compare the cortical activity produced when humans view a pattern of small squares moving incoherently with respect to one another and when the same pattern moves coherently and unidirectionally. A stationary version of the stimulus acted as a con...

journal_title：NeuroImage

authors： McKeefry DJ,Watson JD,Frackowiak RS,Fong K,Zeki S

更新日期：1997-01-01 00:00:00

abstract：:The intention of our study was to compare functional magnetic resonance imaging (fMRI) with positron emission tomography (PET). We used the same force-related motor paradigm for both techniques, which allows for quantification of stimulus intensity. Regional cerebral blood flow (rCBF) was determined with PET in six ma...

journal_title：NeuroImage

authors： Dettmers C,Connelly A,Stephan KM,Turner R,Friston KJ,Frackowiak RS,Gadian DG

更新日期：1996-12-01 00:00:00

abstract：:Magnetic resonance imaging (MRI) has become an established and invaluable tool in the diagnosis of numerous diseases through its ability to show pathologic contrast in images of soft tissue. More recently, MRI has found application in the study of organ function, principally in the brain and heart. This article deals ...

journal_title：NeuroImage

authors： Jezzard P,Song AW

更新日期：1996-12-01 00:00:00

abstract：:Structural neuroimaging has been used to correlate lesional patterns with the cognitive profile of patients with multiple sclerosis (MS), especially for "frontal" dysfunction. However, a clear-cut anatomical explanation has yet to be found for the long-term memory deficit which is a hallmark of MS cognitive impairment...

journal_title：NeuroImage

authors： Paulesu E,Perani D,Fazio F,Comi G,Pozzilli C,Martinelli V,Filippi M,Bettinardi V,Sirabian G,Passafiume D,Anzini A,Lenzi GL,Canal N,Fieschi C

更新日期：1996-10-01 00:00:00

abstract：:We evaluated the cholinergic mechanism underlying focal cortical vascular response to neuronal activation, using positron emission tomography for use on animals to measure cerebral blood flow and glucose metabolism activation upon vibrotactile stimulation in cats. Bromopyruvate, which blocks acetylcholine synthesis th...

journal_title：NeuroImage

authors： Fukuyama H,Ouchi Y,Matsuzaki S,Ogawa M,Yamauchi H,Nagahama Y,Kimura J,Yonekura Y,Shibasaki H,Tsukada H

更新日期：1996-06-01 00:00:00

abstract：:Cortical activation during arithmetic calculation (silent subtraction by sevens) was compared to that observed during a control condition for which subjects were required to count forward by ones. Nine normal subjects underwent 1.5-T functional magnetic resonance imaging while performing these tasks. All subjects show...

journal_title：NeuroImage

authors： Rueckert L,Lange N,Partiot A,Appollonio I,Litvan I,Le Bihan D,Grafman J

更新日期：1996-04-01 00:00:00

abstract：:Transcranial magnetic stimulation with a focal coil was used to map the cortical representation of a hand muscle in four healthy subjects. In each subject, the three-dimensional locations of the magnetic stimulation positions and about 400 positions on the surface of the head were digitized. The amplitude-weighted cen...

journal_title：NeuroImage

authors： Wassermann EM,Wang B,Zeffiro TA,Sadato N,Pascual-Leone A,Toro C,Hallett M

更新日期：1996-02-01 00:00:00

abstract：:We present an experimental evaluation of a new algorithm for the detection of activated areas in brain functional maps. The new algorithm, named HMSD, is based on a hierarchical multiscale description of the difference image in terms of connected objects. Size and magnitude of each object are simultaneously tested wit...

journal_title：NeuroImage

authors： Crivello F,Tzourio N,Poline JB,Woods RP,Mazziotta JC,Mazoyer B

更新日期：1995-12-01 00:00:00

abstract：:Friston et al. (1995, NeuroImage 2:45-53) presented a method for detecting activations in fMRI time-series based on the general linear model and a heuristic analysis of the effective degrees of freedom. In this communication we present corrected results that replace those of the previous paper and solve the same probl...

journal_title：NeuroImage

authors： Worsley KJ,Friston KJ

更新日期：1995-09-01 00:00:00

abstract：:Alzheimer's disease (AD) involves selective loss of muscarinic m2, but not m1, subtype neuroreceptors in cortical and hippocampal regions of the human brain. Emission tomographic study of the loss of m2 receptors in AD is limited by the fact that there is currently no available m2-selective radioligand which can penet...

journal_title：NeuroImage

authors： McRee RC,Boulay SF,Sood VK,Cohen EI,Cohen VI,Gitler MS,Zeeberg BR,Gibson RE,Reba RC

更新日期：1995-03-01 00:00:00

abstract：:Magnetic resonance imaging (MRI) has been performed to determine the efficacy of hyperbaric oxygen treatment (HBO) on experimental allergic encephalomyelitis (EAE) in Lewis rats. The animals were exposed for 2 x 3 h in a 24-h period at 2 ATA pure O2. Three HBO treatment protocols were used: a 10-day preventive treatme...

journal_title：NeuroImage

authors： Namer IJ,Steibel J,Poulet P,Mauss Y,Armspach JP,Eclancher B,Chambron J

更新日期：1994-11-01 00:00:00

abstract：:Developments in imaging technology have made three-dimensional visualization of internal brain structures possible with excellent resolution. Since improved visualization implies improved measurement, these advances hold promise to more accurately measure the volumes of internal structures. As new technologies and tec...

journal_title：NeuroImage

authors： Arndt S,Swayze V,Cizadlo T,O'Leary D,Cohen G,Yuh WT,Ehrhardt JC,Andreasen NC

更新日期：1994-06-01 00:00:00

abstract：:Golgi-impregnated neurons of the human or animal central nervous system were studied with a confocal laser scanning microscope (CLSM). The scanning properties (optical sectioning of the specimen) offered by the CLSM and the capacity of metal granules to reflect the laser beam allow a three-dimensional reconstruction o...

journal_title：NeuroImage

authors： Tredici G,Di Francesco A,Miani A Jr,Pizzini G

更新日期：1993-09-01 00:00:00